Premium Albendazole Oxide from Kaifeng Darui Pharmaceutical
Kaifeng Darui Pharmaceutical Co., Ltd. is a leading manufacturer and supplier of high-quality Albendazole Oxide (CAS 54029-12-8), also known as Ricobendazole or Albendazole sulfoxide. As a premier pharmaceutical raw material provider, we specialize in the production of this essential antiparasitic active pharmaceutical ingredient with a minimum purity of 99.0%. Our state-of-the-art manufacturing facilities and stringent quality control processes ensure that our Albendazole Oxide meets the highest international standards for pharmaceutical applications in both human and veterinary medicine.
Albendazole Oxide (C₁₂H₁₅N₃O₃S) is a critical metabolite of Albendazole and serves as a key component in various antiparasitic formulations worldwide. With a molecular weight of 281.33, this white to off-white crystalline powder is recognized for its effectiveness against a wide range of parasitic infections. At Kaifeng Darui Pharmaceutical, we pride ourselves on delivering consistent, high-quality Albendazole Oxide to pharmaceutical companies, research institutions, and veterinary product manufacturers globally.
Our commitment to excellence extends beyond just manufacturing. We offer comprehensive services including custom synthesis, specialized processing, and neutral large packaging options to meet the diverse needs of our clients. Whether you require small quantities for research purposes or bulk orders for commercial production, our team is equipped to deliver solutions tailored to your specific requirements.
Product Information
Albendazole Oxide: Chemical Properties and Specifications
Albendazole Oxide, chemically known as Methyl [5-(propane-1-sulfinyl)-1H-benzoimidazol-2-yl]-carbamate, is a benzimidazole derivative with powerful antiparasitic properties. Our pharmaceutical-grade Albendazole Oxide is manufactured to exacting standards, ensuring a minimum purity of 99.0% when calculated on a dry basis. This high-purity standard makes our product ideal for pharmaceutical formulations where quality and consistency are paramount.
The physical characteristics of our Albendazole Oxide include:
Appearance: White or off-white crystalline powder Odor: Odorless Solubility: Slightly soluble in ethanol, practically insoluble in acetone and water, readily soluble in glacial acetic acid and sodium hydroxide solution Molecular Formula: C₁₂H₁₅N₃O₃S Molecular Weight: 281.33 CAS Number: 54029-12-8 Melting Point: Consistent with pharmaceutical grade standards Loss on Drying: Not more than 0.5% Residue on Ignition: Not more than 0.2% Iron Content: Not more than 0.003%
Our quality control laboratory conducts comprehensive testing on each batch, including identity confirmation through infrared spectroscopy, HPLC analysis for purity assessment, and specific tests for related substances. The absorption coefficient (E) at 294nm wavelength ranges from 542 to 576, ensuring consistent potency across all production batches. This rigorous testing protocol guarantees that our Albendazole Oxide meets or exceeds all relevant pharmacopoeial standards.
Pharmaceutical Applications and Therapeutic Uses
Albendazole Oxide (Ricobendazole) is the main active metabolite of Albendazole, a broad-spectrum anthelmintic medication included in the World Health Organization’s List of Essential Medicines. As a pharmaceutical raw material, our high-purity Albendazole Oxide serves as a critical ingredient in the formulation of various antiparasitic medications used in both human and veterinary medicine.
In pharmaceutical applications, Albendazole Oxide functions by binding to the colchicine-binding site of β-tubulin, preventing its polymerization. This mechanism disrupts the cytoskeletal structure of parasitic cells, inhibiting glucose uptake and depleting glycogen stores, ultimately leading to energy depletion and parasite death. Notably, Albendazole Oxide exhibits greater affinity for parasitic β-tubulin compared to mammalian tubulin, contributing to its selective toxicity and favorable safety profile.
The therapeutic applications of formulations containing Albendazole Oxide include treatment for:
- Intestinal parasitic infections including roundworms, pinworms, hookworms, and whipworms
- Tissue parasitic infections such as cysticercosis and hydatid disease
- Systemic helminthic infections
- Various veterinary parasitic conditions in livestock and companion animals
Recent research has also explored potential applications beyond antiparasitic use, including investigations into anticancer properties. Studies have shown that Albendazole Oxide can induce apoptosis in certain cancer cell lines, possibly by arresting the cell cycle at the G2/M phase, opening new avenues for pharmaceutical research and development.
Advanced Manufacturing Processes at Kaifeng Darui Pharmaceutical
At Kaifeng Darui Pharmaceutical Co., Ltd., we employ advanced manufacturing technologies and processes to produce Albendazole Oxide of exceptional quality. Our production facilities are designed in accordance with international Good Manufacturing Practice (GMP) standards, ensuring consistent quality across all production batches. The manufacturing process for our Albendazole Oxide involves sophisticated synthetic pathways and purification techniques that have been refined through years of pharmaceutical manufacturing expertise.
Our production capabilities include multi-ton annual capacity, allowing us to meet both small-scale research needs and large commercial orders. The manufacturing process is continuously monitored through in-process controls, with each step validated to ensure optimal yield and purity. Our experienced team of chemists and production specialists oversees every aspect of the manufacturing process, from raw material selection to final product packaging.
Environmental responsibility is integral to our manufacturing philosophy. We have implemented sustainable practices throughout our production processes, including solvent recovery systems, waste reduction initiatives, and energy-efficient equipment. These measures not only reduce our environmental footprint but also contribute to cost-effectiveness, allowing us to offer competitive pricing without compromising on quality.
Quality Assurance and Regulatory Compliance
Quality is the cornerstone of our operations at Kaifeng Darui Pharmaceutical. Our comprehensive quality management system encompasses all aspects of production, from incoming raw material inspection to final product release. Each batch of Albendazole Oxide undergoes rigorous testing according to established pharmacopoeial methods and our enhanced internal specifications.
Our quality control laboratory is equipped with state-of-the-art analytical instruments, including High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), Infrared Spectroscopy (IR), and Ultraviolet-Visible Spectrophotometry (UV-Vis). These advanced analytical capabilities enable precise determination of identity, purity, and potency for every batch of Albendazole Oxide we produce.
Regulatory compliance is paramount in pharmaceutical manufacturing, and Kaifeng Darui Pharmaceutical maintains all necessary certifications and approvals for the production of pharmaceutical raw materials. Our operations comply with international standards and regulations, including those of major pharmaceutical markets worldwide. We maintain comprehensive documentation for all production batches, facilitating traceability and supporting our customers’ regulatory submissions.
Customized Production and Processing Services
Kaifeng Darui Pharmaceutical offers tailored production and processing services to meet the specific requirements of our diverse client base. We understand that different pharmaceutical applications may require variations in specifications, particle size, or other physical characteristics of Albendazole Oxide. Our flexible manufacturing capabilities allow us to customize production parameters according to client specifications while maintaining our stringent quality standards.
Our customization services include:
Custom Synthesis: For clients requiring modified molecular structures or specific impurity profiles, our R&D team can develop custom synthetic routes to meet these specialized needs. We work closely with clients from initial concept through scale-up to commercial production.
Particle Size Modification: We offer various milling and micronization options to achieve specific particle size distributions, enhancing the performance of Albendazole Oxide in different formulation types.
Specialized Analytical Testing: Beyond standard quality control testing, we can perform additional analyses based on client requirements, including specialized impurity profiling, polymorphism studies, and stability assessments.
Process Development and Optimization: For clients looking to improve their own formulation processes, our technical team provides expert consultation on process optimization using our high-quality Albendazole Oxide.
Each customization project begins with a detailed consultation to understand specific requirements, followed by feasibility assessment, development work, and scale-up. Our experienced project management team ensures smooth execution and timely delivery of customized products.
Packaging and Supply Chain Solutions
Kaifeng Darui Pharmaceutical offers versatile packaging options to accommodate various transportation, storage, and handling requirements. Our neutral large packaging solutions are designed to protect product integrity while meeting international shipping regulations for pharmaceutical raw materials.
Available packaging options include:
Standard Packaging: High-quality fiber drums with polyethylene liners, available in various sizes from 5kg to 50kg Neutral Packaging: Unmarked containers with customizable labeling for clients who prefer discreet shipping or plan to repackage under their own brand Bulk Packaging: Large-volume options for industrial-scale users, including super sacks and customized containers Specialized Packaging: Moisture-resistant, light-protective, or temperature-controlled packaging for sensitive applications
Our global logistics network ensures reliable delivery to destinations worldwide, with full tracking capabilities and documentation support for international shipping. We maintain strategic inventory levels of Albendazole Oxide to accommodate urgent orders and minimize lead times for our clients.
For clients with ongoing requirements, we offer supply agreement options with scheduled deliveries, ensuring consistent availability of material for production planning. Our customer service team provides responsive support throughout the ordering, production, and delivery process, serving as a single point of contact for all supply chain inquiries.
Innovation and Continuous Improvement
Research and development form the foundation of our operations at Kaifeng Darui Pharmaceutical. Our dedicated R&D team continuously works on improving synthesis routes, enhancing product purity, and developing more sustainable manufacturing processes for Albendazole Oxide. This commitment to innovation enables us to stay at the forefront of pharmaceutical raw material manufacturing while offering increasingly competitive products to our clients.
Recent developments in our Albendazole Oxide production include:
Enhanced Synthetic Pathways: Implementation of more efficient synthetic routes that reduce the number of steps, increase overall yield, and minimize environmental impact Improved Purification Techniques: Development of advanced purification methods that consistently achieve higher purity levels while reducing solvent usage Green Chemistry Initiatives: Adoption of environmentally friendly reagents and catalysts that maintain product quality while reducing ecological footprint Analytical Method Development: Creation of more sensitive and specific analytical methods for impurity detection and characterization
Our R&D capabilities extend beyond process improvements to include collaborative research with pharmaceutical partners. We welcome opportunities to participate in joint development projects, particularly those focused on novel applications or formulations of Albendazole Oxide.
Technical Support and Documentation
Kaifeng Darui Pharmaceutical provides comprehensive technical support to assist clients in optimizing the use of our Albendazole Oxide in their formulations and processes. Our technical service team includes experienced pharmaceutical scientists and engineers who understand the challenges of drug formulation and can provide valuable insights for product development.
Technical support services include:
Comprehensive Documentation: Each batch of Albendazole Oxide is accompanied by detailed certificates of analysis, safety data sheets, and regulatory documentation to support our clients’ quality systems and regulatory filings Formulation Assistance: Technical guidance on incorporating our Albendazole Oxide into various pharmaceutical dosage forms, including tablets, suspensions, and veterinary preparations Stability Data: Access to long-term and accelerated stability studies to support shelf-life determinations and storage recommendations Regulatory Support: Assistance with regulatory questions related to our Albendazole Oxide, including preparation of documentation for Drug Master Files (DMFs) and similar submissions
Our commitment to technical support extends throughout the product lifecycle, from initial sampling and evaluation through commercial production and ongoing supply. We view our client relationships as partnerships, with shared goals of producing high-quality, effective pharmaceutical products for global markets.
Partner with Kaifeng Darui Pharmaceutical
Choosing Kaifeng Darui Pharmaceutical as your supplier of Albendazole Oxide means partnering with a company committed to quality, reliability, and customer satisfaction. Our extensive experience in pharmaceutical raw material manufacturing, combined with our focus on continuous improvement and customer service, makes us the preferred choice for pharmaceutical companies worldwide.
We invite you to experience the Kaifeng Darui difference through:
Product Sampling: Request samples of our Albendazole Oxide to evaluate its quality and suitability for your specific applications Technical Consultation: Discuss your requirements with our technical team to identify the optimal specifications and services for your needs Custom Quotations: Receive personalized pricing based on your quantity requirements, specifications, and delivery timeline Facility Audits: Arrange a visit to our manufacturing facilities to observe our operations and quality systems firsthand
Our global presence ensures that wherever you are located, we can provide responsive service and reliable supply of Albendazole Oxide. With distribution centers in key markets and an efficient logistics network, we deliver our products promptly to destinations worldwide.
How to Order
Ordering Albendazole Oxide from Kaifeng Darui Pharmaceutical is straightforward and efficient. Our customer service team is available to guide you through the process and answer any questions you may have.
To place an order or request information:
Email:info@daruipharm.com
Phone: +86-13837178289
Website:https://daruipharm.com/
Online Inquiry Form: Available on our website for specific product or service inquiries
For new customers, we recommend beginning with a consultation to understand your specific requirements and provide appropriate recommendations. For returning customers, we offer streamlined reordering processes and the option to establish supply agreements for regular deliveries.
Kaifeng Darui Pharmaceutical Co., Ltd. is your trusted partner for high-quality Albendazole Oxide and other pharmaceutical raw materials. Contact us today to discover how our products and services can support your pharmaceutical manufacturing needs.
Albendazole Oxide CAS 54029-12-8 Albendazole sulfoxide Anthelmintic API Kaifeng Darui Pharmaceutical Pharmaceutical raw material Ricobendazole