Atropine Sulfate, with the CAS number 5908-99-6, is a widely used pharmaceutical compound with a broad spectrum of medical applications. Produced by Kaifeng Darui Pharmaceutical Co., Ltd., a leading name in China's pharmaceutical manufacturing sector, this compound is recognized globally for its purity, efficacy, and compliance with international pharmacopoeia standards.
This article dives deep into the production, specifications, applications, safety, and global market presence of Atropine Sulfate from Kaifeng Darui. Whether you're a buyer, distributor, or researcher, this comprehensive guide offers everything you need to know.
Table of Contents
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What is Atropine Sulfate?
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CAS Number 5908-99-6: Chemical Identity and Specifications
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Applications and Therapeutic Uses
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About Kaifeng Darui Pharmaceutical Co., Ltd.
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Regulatory and Quality Certifications
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Packaging and Storage Information
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Global Demand and Export Markets
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Competitive Advantage of Kaifeng Darui
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Safety Profile and Handling Precautions
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How to Source Atropine Sulfate
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Conclusion
1. What is Atropine Sulfate?
Atropine Sulfate is a tropane alkaloid derived from plants like Atropa belladonna and other Solanaceae species. As a muscarinic antagonist, it inhibits parasympathetic nerve impulses, making it effective in various medical emergencies and treatments.
Atropine is used to treat:
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Bradycardia (slow heart rate)
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Organophosphate poisoning
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Preoperative secretion reduction
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Certain eye disorders (mydriasis and cycloplegia)
The sulfate salt form improves solubility, making it ideal for injectable solutions and ophthalmic preparations.
2. CAS Number 5908-99-6: Chemical Identity and Specifications
Chemical Properties:
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Chemical Name: Atropine Sulfate
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CAS Number: 5908-99-6
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Molecular Formula: (C17H23NO3)2·H2SO4
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Molecular Weight: 694.84 g/mol
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Appearance: White crystalline powder
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Solubility: Freely soluble in water and alcohol
Pharmacopoeia Standards:
Kaifeng Darui’s Atropine Sulfate complies with:
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USP (United States Pharmacopeia)
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EP (European Pharmacopoeia)
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CP (Chinese Pharmacopoeia)
Quality Specifications:
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Purity: ≥ 99%
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Loss on drying: ≤ 1.0%
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Sulfate content: In accordance with monograph standards
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Heavy metals: ≤ 10 ppm
These standards ensure the product's consistency and safety across global markets.
3. Applications and Therapeutic Uses
Ophthalmology:
Used in diagnostic procedures for pupil dilation (mydriasis) and accommodation paralysis (cycloplegia).
Anesthesia:
Reduces salivation and bronchial secretions during surgery. Also prevents vagal reflexes during intubation.
Cardiology:
Administered intravenously for bradycardia to increase heart rate during cardiac emergencies.
Toxicology:
Acts as an antidote to organophosphate poisoning, such as insecticide or nerve agent exposure.
Gastrointestinal Disorders:
Relieves smooth muscle spasms in the gastrointestinal tract, treating irritable bowel syndrome or peptic ulcers.
4. About Kaifeng Darui Pharmaceutical Co., Ltd.
Kaifeng Darui Pharmaceutical Co., Ltd. is a high-tech pharmaceutical company based in Kaifeng, Henan Province, China. Established with a mission to deliver GMP-compliant, API-grade pharmaceuticals, Darui has earned a strong reputation in both domestic and global markets.
Core Strengths:
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ISO-certified production facilities
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Advanced R&D capabilities
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Export-oriented business model
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Transparent supply chain management
Darui’s commitment to pharmaceutical quality and customer satisfaction makes them a reliable supplier of Atropine Sulfate worldwide.
5. Regulatory and Quality Certifications
Kaifeng Darui holds multiple international certifications that enhance buyer confidence and market access:
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Good Manufacturing Practices (GMP)
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ISO 9001:2015 Quality Management System
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Certificate of Suitability (CEP) – where applicable
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DMF Filing (Drug Master File available upon request)
These credentials ensure compliance with stringent quality assurance protocols in regulated markets like the EU, US, and Japan.
6. Packaging and Storage Information
Packaging Details:
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Standard Packing: 1kg/Aluminum foil bag, 25kg/Fiber drum
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Custom Packaging: Available upon request
Storage Conditions:
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Store in a cool, dry, and well-ventilated place
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Protect from light and moisture
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Shelf life: 2 years under recommended conditions
Proper packaging ensures the integrity and potency of Atropine Sulfate throughout its shelf life and transit period.
7. Global Demand and Export Markets
The demand for Atropine Sulfate is rising across multiple sectors—hospitals, emergency care units, pharmaceutical manufacturers, and military organizations.
Key Export Destinations:
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United States
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Germany
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India
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Brazil
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South Africa
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Saudi Arabia
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Vietnam
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Mexico
Kaifeng Darui has successfully partnered with importers, wholesalers, and contract manufacturers in over 30 countries, meeting bulk and small-batch demands with ease.
8. Competitive Advantage of Kaifeng Darui
What sets Kaifeng Darui Pharmaceutical Co., Ltd. apart from competitors?
1. Consistent Product Quality
Strict adherence to international standards ensures a high level of batch-to-batch consistency.
2. Scalable Production
Modern facilities allow for large-scale manufacturing and timely delivery.
3. Technical Support
Customers are provided with full technical dossiers, COAs, and DMFs to simplify the registration process in regulated markets.
4. Customized Services
Kaifeng Darui offers tailored solutions in formulation, logistics, and regulatory compliance.
9. Safety Profile and Handling Precautions
Toxicology:
Atropine Sulfate should only be used under medical supervision due to its narrow therapeutic index. Overdose can lead to dry mouth, blurred vision, tachycardia, hallucinations, and urinary retention.
Handling Guidelines:
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Use protective clothing and gloves
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Avoid inhalation and direct skin contact
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Ensure adequate ventilation during handling
First Aid Measures:
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Inhalation: Move to fresh air and seek medical attention
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Skin contact: Wash thoroughly with soap and water
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Eye contact: Rinse with water for at least 15 minutes
Kaifeng Darui provides MSDS (Material Safety Data Sheets) with every shipment to assist customers in compliance and workplace safety.
10. How to Source Atropine Sulfate
Sourcing from Kaifeng Darui Pharmaceutical Co., Ltd. is a smooth and transparent process.
Inquiry Channels:
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Official Website: www.daruipharm.com
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Email: info@daruipharm.com
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Phone: +86-13837178289
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Trade Shows: CPhI Worldwide, API China, etc.
Minimum Order Quantity (MOQ):
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Usually 1kg for API orders
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Larger quantities available at competitive bulk pricing
Kaifeng Darui also supports sample requests, allowing clients to validate quality before placing a full order.
11. Conclusion
Atropine Sulfate (CAS: 5908-99-6) continues to play a critical role in modern medicine, from emergency cardiac care to ophthalmology and toxicology. With Kaifeng Darui Pharmaceutical Co., Ltd. as a trusted supplier, businesses and healthcare providers gain access to a pharmaceutical-grade product backed by decades of expertise and regulatory compliance.
Whether you're a formulation company, hospital procurement manager, or API wholesaler, choosing Kaifeng Darui means choosing reliability, quality, and excellence.
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