Ethacridine Lactate Monohydrate, with the CAS number 6402-23-9, is a remarkable aromatic organic compound derived from acridine, celebrated for its multifaceted applications in pharmaceuticals, research, and environmental sciences. Known by synonyms such as Rivanol, Acrinol, and Ethodin, this vibrant yellow crystalline substance is a flagship product of Kaifeng Darui Pharmaceutical Co., Ltd., a leading manufacturer committed to delivering high-quality pharmaceutical intermediates and fine chemicals. This article delves into the properties, applications, and significance of Ethacridine Lactate Monohydrate, highlighting why Kaifeng Darui Pharmaceutical stands out in its production.
Understanding Ethacridine Lactate Monohydrate
Ethacridine Lactate Monohydrate (C18H23N3O5, molecular weight: 361.398) is a water-soluble, acridine-based compound with a melting point of 243–245°C. Its chemical structure, characterized by a 7-ethoxyacridine-3,9-diamine core combined with lactic acid and a hydrate, imparts unique properties that make it invaluable across various domains. The compound’s fluorescence and DNA-intercalating capabilities are particularly notable, enabling its use in both clinical and non-clinical settings. Kaifeng Darui Pharmaceutical Co., Ltd. ensures that their Ethacridine Lactate Monohydrate meets stringent purity standards (≥98%), making it a reliable choice for researchers and manufacturers.
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- CAS Number: 6402-23-9
- Molecular Formula: C15H15N3O·C3H6O3·H2O
- Molecular Weight: 361.398 g/mol
- Appearance: Yellow crystalline powder
- Solubility: Soluble in water and alcohol
- Melting Point: 243–245°C
- Stability: Stable under ambient conditions, with recommended storage at 0–4°C for short-term and -20°C for long-term
These properties, combined with its low toxicity and non-carcinogenic nature, make Ethacridine Lactate Monohydrate a versatile compound for diverse applications.
Applications of Ethacridine Lactate Monohydrate
Ethacridine Lactate Monohydrate’s utility spans pharmaceuticals, microbiology, and environmental research. Below are its primary applications:
1. Antiseptic Agent
One of the most prominent uses of Ethacridine Lactate Monohydrate is as an antiseptic agent. Its efficacy against Staphylococcus aureus and other gram-positive cocci makes it a valuable tool in medical and laboratory settings. The compound disrupts bacterial cell processes, ensuring effective sterilization. Kaifeng Darui Pharmaceutical’s high-purity Ethacridine Lactate Monohydrate is ideal for producing antiseptic formulations, ensuring safety and reliability in clinical applications.
2. DNA Intercalation and Research
Ethacridine Lactate Monohydrate’s ability to intercalate between DNA base pairs makes it a powerful tool in molecular biology. By inserting itself into the DNA helix, it disrupts normal DNA functions, aiding studies on DNA replication, transcription, and molecular binding dynamics. This property is leveraged in fluorescence microscopy, where its fluorescent nature allows researchers to visualize DNA processes within cells. Kaifeng Darui’s product is widely used in non-clinical research, particularly in chemistry and environmental sciences, to explore nucleic acid interactions.
3. Abortifacient Applications
In certain medical contexts, Ethacridine Lactate Monohydrate is used as an abortifacient, particularly for second-trimester pregnancy termination. Studies, such as those by Gupta et al. (1993), highlight its safety and efficacy when administered intra-amniotically. It increases prostaglandin E levels and reduces estriol excretion, facilitating fetal expulsion. Kaifeng Darui Pharmaceutical ensures that their product meets the necessary quality standards for such sensitive applications, though its use is strictly for research and controlled medical purposes.
4. Poly(ADP-ribose) Glycohydrolase (PARG) Inhibition
Recent research, including a study by Rotin et al. (2016), has identified Ethacridine Lactate Monohydrate as a PARG inhibitor, with potential applications in treating acute myeloid leukemia when combined with drugs like Erlotinib. This emerging role underscores the compound’s versatility and the importance of high-quality production by manufacturers like Kaifeng Darui.
5. Environmental and Biochemical Studies
The compound’s fluorescence properties and DNA-binding capabilities are also utilized to assess the environmental impact of DNA-binding chemicals. Researchers use Ethacridine Lactate Monohydrate to study how such substances interact with biological systems and persist in ecosystems, providing insights into their ecological and biochemical behavior.
Kaifeng Darui Pharmaceutical Co., Ltd.: A Trusted Manufacturer
Kaifeng Darui Pharmaceutical Co., Ltd. is a renowned name in the pharmaceutical industry, specializing in the production of high-quality APIs, intermediates, and fine chemicals. Their Ethacridine Lactate Monohydrate (CAS: 6402-23-9) is manufactured under strict quality control measures, ensuring purity, consistency, and compliance with international standards. The company’s state-of-the-art facilities and commitment to innovation make it a preferred supplier for researchers and manufacturers worldwide.
Why Choose Kaifeng Darui?
- High Purity: Ethacridine Lactate Monohydrate with ≥98% purity, verified through rigorous testing.
- Quality Assurance: Comprehensive Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS) are available.
- Global Reach: Efficient supply chain and prompt delivery to meet client needs.
- Customer Support: Dedicated assistance for product inquiries, CoA requests, and technical support.
- Sustainability: Environmentally responsible manufacturing practices.
Safety and Handling
Ethacridine Lactate Monohydrate is classified as a non-hazardous chemical for shipping and handling under ambient conditions. However, it is intended for research use only and not for diagnostic or therapeutic purposes in humans. Proper storage at 0–4°C for short-term use or -20°C for long-term preservation is recommended to maintain stability. Kaifeng Darui provides detailed safety data sheets to guide users on safe handling and disposal.
Market Insights and Future Prospects
The global demand for Ethacridine Lactate Monohydrate is driven by its applications in antiseptics, molecular biology, and medical research. The pharmaceutical intermediates market, valued at billions annually, continues to grow, with compounds like Ethacridine Lactate Monohydrate playing a pivotal role. Kaifeng Darui Pharmaceutical is well-positioned to capitalize on this trend, offering a product that meets the needs of diverse industries.
Emerging research into PARG inhibition and antiviral applications, such as its potential against SARS-CoV-2 (Li et al.), suggests a bright future for Ethacridine Lactate Monohydrate. As new therapeutic and research applications are explored, Kaifeng Darui’s commitment to quality will ensure its product remains at the forefront of innovation.
Conclusion
Ethacridine Lactate Monohydrate (CAS: 6402-23-9) is a versatile compound with significant applications in antiseptics, molecular biology, medical procedures, and environmental research. Produced by Kaifeng Darui Pharmaceutical Co., Ltd., this high-purity product exemplifies quality and reliability, making it a preferred choice for researchers and manufacturers worldwide. Whether you’re studying DNA interactions, developing antiseptic formulations, or exploring new therapeutic avenues, Kaifeng Darui’s Ethacridine Lactate Monohydrate is a trusted partner in advancing scientific and medical progress.
For more information or to request a Certificate of Analysis, contact Kaifeng Darui Pharmaceutical Co., Ltd. today and discover the potential of Ethacridine Lactate Monohydrate.
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