Albendazole Tablets are a premium antiparasitic medication formulated to combat gastrointestinal worms, tapeworms, and flukes in livestock and companion animals. Kaifeng Darui Pharmaceutical Co., Ltd. produces these tablets under strict GMP standards, ensuring efficacy, safety, and compliance with global veterinary regulations.
Key Specifications:
- Active Ingredient: Albendazole (C₁₂H₁₅N₃O₂S)
- Available Strengths: 25mg, 50mg, 0.1g, 0.2g, 0.3g
- Applications: Treats nematodes, cestodes, and trematodes in cattle, sheep, poultry, swine, and dogs.
- Certifications: GMP-compliant Grade D cleanrooms, ISO environmental systems.
Why Choose Kaifeng Darui’s Albendazole Tablets?
1. Uncompromising Quality Assurance
- Advanced QC Labs: Shimadzu HPLC, UV-Vis spectrophotometry, and stability testing guarantee 100% compliance with pharmacopeial standards.
- Eco-Friendly Production: 150t/d wastewater treatment and RCO exhaust systems meet national emission standards.
2. Customized Production & Packaging
- ODM/OEM Services: Tailor dosage forms, excipients, or tablet markings to your brand’s needs.
- Neutral Large Packaging: Bulk orders available in tamper-proof, shelf-stable packaging (1kg–25kg).
- Contract Manufacturing: From R&D to commercialization—leverage our 700㎡ API synthesis facility and 12+ utility patents.
3. Expertise in Veterinary APIs
- Innovation-Driven: Partnerships with Henan Academy of Sciences and Pingdingshan University for process optimization.
- Proven Formulations: Patented catalytic systems for Albendazole synthesis enhance purity (>99.5%) and bioavailability.
Key Services for Global Partners
- Custom Synthesis: Develop proprietary Albendazole derivatives or combination therapies.
- Regulatory Support: Documentation for FDA, EMA, and WHO compliance.
- Logistics Solutions: Doorstep delivery with cold-chain management for temperature-sensitive shipments.
Technical Highlights
Pharmacological Profile
- Mechanism: Inhibits microtubule synthesis in parasites, leading to immobility and death.
- Dosage Guidelines:
- Cattle/Sheep: 10–15mg/kg body weight
- Poultry/Swine: 10–20mg/kg
- Dogs: 25–50mg/kg (avoid prolonged use due to anemia risk)
Safety & Compliance
- Residue Control: Adheres to strict withdrawal periods (e.g., 14 days for cattle, 60-hour milk discard).
- Storage: Maintain in sealed, dry conditions below 25°C.
Sustainability & Social Responsibility
Kaifeng Darui Pharma prioritizes green manufacturing and ethical practices:
- Zero-Waste Initiatives: 98% solvent recovery in synthesis processes.
- Community Impact: Supports rural livestock health programs in Henan Province.
Contact Us for Partnerships
Custom Orders: Submit your requirements for formulation, packaging, or MOQ.
Global Distributors: Join our network to access cost-quality competitive APIs.
Here is the translated version of Doc2 (Albendazole Tablets technical specifications) into English, formatted for clarity and accuracy:
Albendazole Tablets
Composition
Each tablet contains Albendazole (C₁₂H₁₅N₃O₂S) within 90.0%–110.0% of the labeled amount.
Characteristics
- Appearance: Off-white tablets.
Identification
- Test 1: Grind a sample equivalent to 0.2g of Albendazole, dissolve in 30ml ethanol via water bath heating, filter, and evaporate the filtrate to dryness. Conduct tests per Albendazole identification methods (1) and (2); results must match reference standards.
- Test 2: Using the solution from the “Assay” section, perform UV-Vis spectrophotometry (Appendix 0401). Maximum absorption at 295nm and minimum absorption at 277nm must be observed.
Tests
Dissolution
- Method: Dissolution test (Appendix 0931, Method 2) using 900ml 0.1mol/L HCl as medium, 75rpm rotation speed.
- Procedure: After 45 minutes, filter the solution. Dilute the filtrate with 0.1mol/L NaOH to 10μg/ml as the test solution. Prepare a reference solution by dissolving 20mg Albendazole (accurately weighed) in 5ml 2% HCl-methanol, dilute with 0.1mol/L HCl to 100ml, then further dilute 5ml to 100ml with 0.1mol/L NaOH.
- Measurement: Measure absorbance at 308nm. Dissolution must be ≥65% of labeled amount.
Other Requirements: Complies with tablet specifications (Appendix 0101).
Assay
- Weigh 20 tablets, grind to powder, and accurately weigh a sample equivalent to 20mg Albendazole.
- Dissolve in 10ml glacial acetic acid, dilute with ethanol to 100ml, filter, and dilute 5ml filtrate to 100ml with ethanol.
- Perform UV-Vis spectrophotometry (Appendix 0401) at 295nm. Calculate content using absorption coefficient (E₁%₁cm) of 444 for C₁₂H₁₅N₃O₂S.
Indications
Anthelmintic for treating nematodes, cestodes, and trematodes in livestock and poultry.
Dosage & Administration
Oral administration (Albendazole equivalent):
- Horses: 5–10mg/kg body weight
- Cattle/Sheep: 10–15mg/kg
- Swine: 5–10mg/kg
- Poultry: 10–20mg/kg
- Dogs: 25–50mg/kg
Adverse Reactions
- Anorexia may occur in dogs with prolonged use (50mg/kg twice daily).
- Risk of aplastic anemia in dogs.
- Teratogenic and embryotoxic effects in early-pregnancy animals.
Precautions
- Avoid use in cattle and sheep during the first 45 days of gestation.
Withdrawal Periods
- Cattle: 14 days
- Sheep: 4 days
- Swine: 7 days
- Poultry: 4 days
- Milk Discard: 60 hours
Specifications
25mg, 50mg, 0.1g, 0.2g, 0.3g
Storage
Store in airtight containers.
Kaifeng Darui Pharmaceutical Co., Ltd. – Innovating for Healthier Livestock and a Healthier Planet.
