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As of May 16, 2025, the veterinary drug active pharmaceutical ingredient (API) market continues to exhibit a stable operational landscape, characterized by narrow price fluctuations for most categories. This report delves into the latest market dynamics, key product trends, and strategic insights for industry stakeholders.
I. Market Overview: Steady Demand Meets Controlled Supply
The market has maintained a balanced rhythm, with mainstream manufacturers adhering to consistent supply strategies and trade channels focusing on inventory digestion. While procurement demand has gradually picked up, driving moderate market activity, price movements remain constrained, with notable attention on products like oxytetracycline hydrochloride, amoxicillin, and tilmicosin.
Industry players are advised to monitor production schedules and supply restriction policies closely, adjusting procurement strategies flexibly to mitigate potential risks from sudden market shifts.
II. Category-Specific Market Trends
1. Antibiotics: Mixed Signals Across Subclasses
Penicillins & Amide Alcohols
- Benzylpenicillin Potassium Industrial Salt: Prices held steady at 112–120 yuan/billion units, supported by stable factory quotes and downstream rigid demand procurement.
- Amoxicillin: Market tension rose slightly as supplier inventory controls lengthened delivery cycles, pushing transaction prices to 220–245 yuan/kg with a “moderately bullish” price index.
- Florfenicol: Limited production from major manufacturers kept inventories low, stabilizing prices at 183–205 yuan/kg despite weak terminal demand and cautious trade sentiment.
Tetracyclines & Macrolides: Supply-Driven Price Strength**
- Oxytetracycline Complex: Both raw oxytetracycline (75–85 yuan/kg) and its hydrochloride form (93–105 yuan/kg) saw upward price indices due to sustained manufacturer price hikes and tight trade supplies.
- Doxycycline Hydrochloride (Doxycycline): Stable at 355–370 yuan/kg, driven by upstream cost support and active trade inventory buildup.
- Macrolide Standouts:
- Erythromycin Thiocyanate surged on supply restrictions, trading at 480–515 yuan/kg with an upward price trend.
- Tylosin (305 yuan/kg) and tilmicosin (380 yuan/kg) remained at elevated levels, though trade inquiries slowed amid limited market stock and manufacturer price stands.
2. Other Key Categories: Cost Pressures and Selective Demand
Aminoglycosides: Polarized Performance
- Workhorse products like streptomycin sulfate (272–290 yuan/billion units) and apramycin sulfate (198–220 yuan/kg) held stable on rigid demand, while gentamicin sulfate (veterinary grade) weakened to 1480–1520 yuan/billion units due to low market interest.
Antipyretic Analgesics: Cost-Driven Adjustments
- Analgin led the upward charge, rising to 88–100 yuan/kg as surging upstream raw material costs forced manufacturer price hikes.
- Paracetamol remained range-bound at 25–35 yuan/kg, reflecting stable large-scale production, while carbasalate calcium oscillated at 36–45 yuan/kg amid moderate demand.
Quinolones & Sulfonamides: Steady but Uninspired**
Quinolones like enrofloxacin (190 yuan/kg) and ciprofloxacin (180 yuan/kg) held firm on cost support, while sulfonamides (e.g., sulfachlorpyrazin sodium at 220 yuan/kg) stagnated with “consolidation” trends due to concentrated supply and lukewarm demand.
III. Market Drivers and Strategic Outlook
Supply Dynamics
Manufacturer actions remain pivotal: production cuts, order restrictions, and price stands in key antibiotics (e.g., tetracyclines, macrolides) have created pockets of supply tightness, driving premium pricing for critical APIs. Conversely, oversupply in less-segmented markets (e.g., sulfonamides) has curbed upward momentum.
Demand Trends
Terminal demand skews toward rigidity, with buyers prioritizing inventory optimization over speculative purchases. High-price products like tilmicosin face softer trade interest, while foundational antibiotics maintain steady off-take.
Recommendations for Industry Participants
- Short-Term: Leverage flexible procurement strategies, balancing inventory levels with real-time tracking of manufacturer policies (e.g., production halts, supply restrictions).
- Mid-Term: Diversify sourcing for tight-supply APIs and build contingency plans for cost fluctuations, particularly in categories influenced by upstream chemical raw material prices (e.g., analgin, quinolones).
- Risk Management: Monitor regulatory and environmental policies that may impact manufacturer output, as these remain key wildcards for supply stability.
IV. Conclusion: A Market of Contrasts
May 2025 sees the veterinary API market in a phase of controlled equilibrium—stable overall, yet marked by sharp contrasts between supply-constrained, high-growth segments and oversupplied, stagnant areas. While the majority of products maintain price stability, strategic players can gain an edge by focusing on data-driven procurement, supplier diversification, and proactive risk mitigation. As the market navigates these crosscurrents, agility and foresight will be critical to converting market trends into competitive advantage.
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Analysis of Veterinary Drug API Market Trends (May 16, 2025)
I. Overall Market Overview
- Market Trend: The veterinary drug API market has maintained stable operation recently, with most categories experiencing narrow price fluctuations. Mainstream manufacturers have not significantly adjusted their supply strategies, and trade channels are mainly focused on inventory digestion. Market procurement demand is gradually releasing, with moderate activity. Notable varieties include oxytetracycline hydrochloride, amoxicillin, doxycycline hydrochloride (doxycycline), trimethoprim, and tilmicosin.
- Operational Suggestions: Enterprises should dynamically track manufacturers’ production plans and supply restriction policies based on their own inventory and demand, adjust procurement rhythms flexibly, and prepare in advance for potential market fluctuations.
II. In-Depth Analysis of Key Categories
| Category | Product | Price Range (RMB) | Market Characteristics | Price Index Trend |
|---|---|---|---|---|
| Penicillins | Benzylpenicillin Potassium Industrial Salt | 112–120 yuan/billion units | Stable quotes from mainstream manufacturers; downstream procurement based on demand; moderate market expectations; narrow price fluctuations. | Stable |
| Amoxicillin | 220–245 yuan/kg | Stable factory quotes; supply cycles extended due to supplier inventory control; increasing market attention. | Moderately Bullish | |
| Amide Alcohols | Florfenicol | 183–205 yuan/kg | Mainstream manufacturers maintain production cuts; low market inventory; stable prices; strong wait-and-see sentiment in trade channels; weak terminal demand. | Stable with Volatility |
| Tetracyclines | Oxytetracycline | 75–85 yuan/kg | Continuous price increases and order restrictions by manufacturers; tight trade inventory; firm transaction quotes. | Upward |
| Oxytetracycline Hydrochloride | 93–105 yuan/kg | Same as above. | Upward | |
| Doxycycline Hydrochloride (Doxycycline) | 355–370 yuan/kg | Moderate factory supply; increased trade inventory buildup due to upstream cost support; smooth terminal supply and procurement. | Stable with Volatility | |
| Macrolides | Erythromycin Thiocyanate | 480–515 yuan/kg | Sustained supply restrictions by mainstream manufacturers; moderate trade inventory; tight supply; firm transaction prices. | Upward |
| Tylosin | ~305 yuan/kg | Manufacturers halt quotes and maintain prices; limited market inventory; high prices; slower trade inquiries; high market attention. | Stronger Trend | |
| Tilmicosin | ~380 yuan/kg | Same as Tylosin. | Stronger Trend | |
| Aminoglycosides | Streptomycin Sulfate | 272–290 yuan/billion units | Stable factory quotes; rigid demand support; light trade inquiries. | Stable |
| Apramycin Sulfate | 198–220 yuan/kg | Stable factory quotes; low trade inventory; steady transaction prices. | Stable | |
| Neomycin Sulfate | 155–170 yuan/billion units | Continuous order restrictions and price maintenance by manufacturers; slightly tight ready stock；high transaction prices. | Stable with Volatility | |
| Gentamicin Sulfate (Veterinary) | 1480–1520 yuan/billion units | Concentrated supply channels; low market attention; negotiated transactions. | Weakening | |
| Sulfonamides | Sulfachlorpyrazin Sodium | ~220 yuan/kg | Concentrated upstream supply; stable prices for most varieties; moderate trade inquiries. | Consolidation |
| Sulfadiazine Sodium | ~175 yuan/kg | Same as above. | Consolidation | |
| Sulfamonomethoxine Sodium | ~190 yuan/kg | Same as above. | Consolidation | |
| Quinolones | Enrofloxacin Hydrochloride | ~190 yuan/kg | Concentrated production capacity; factory price support due to upstream cost increases; sudden rise in market attention. | Stable |
| Ciprofloxacin Hydrochloride | ~180 yuan/kg | Same as Enrofloxacin. | Stable | |
| Antipyretic Analgesics | Analgin | 88–100 yuan/kg | Upstream raw material price increases drive production costs; manufacturers raise prices; concentrated circulation inventory. | Upward |
| Paracetamol | 25–35 yuan/kg | Concentrated production capacity; narrow price fluctuations. | Stable | |
| Carbasalate Calcium | 36–45 yuan/kg | Stable factory quotes; moderate market inquiries; high attention. | Volatile | |
| Others | Acetylmethaquine (Dihydroquindine) | 39–49 yuan/kg | Previous supply restrictions and price support; active trade inventory buildup; slower recent transactions; price consolidation. | Stable with Volatility |
| Colistin Sulfate | 113–120 yuan/kg | Stable factory quotes; moderate supply and procurement; narrow price fluctuations. | Stable with Volatility |
III. Key Conclusions
- Supply Side: Many varieties face production cuts, order restrictions, or halted quotes by manufacturers; some (e.g., oxytetracycline, erythromycin thiocyanate) have tight inventory.
- Demand Side: Terminal demand is differentiated, with rigid procurement prevailing; trade inquiries for high-price varieties (e.g., tilmicosin, tylosin) have slowed.
- Price Trends: Over half of the varieties maintain stable price indices; a few see upward trends due to cost pressure or supply tightness (e.g., analgin, oxytetracycline); only veterinary gentamicin sulfate shows a weakening trend.
Recently, the overall operation of the veterinary drug raw material market has remained stable, and the prices of most categories have continued to fluctuate within a narrow range. The supply strategies of mainstream factories have not undergone significant adjustments. The trade channels mainly focus on inventory digestion. The market procurement demand is gradually being released, and the market activity is fairly good. Varieties such as oxytetracycline hydrochloride, amoxicillin, doxycycline, trimethoprim, and tilmicosin are still attracting market attention. It is recommended to dynamically track the production plans and supply restriction policies of factories in combination with your own inventory and demand, flexibly adjust the procurement rhythm, and make advance contingency plans for market fluctuations.
Analysis of Veterinary Drug Raw Material Market
Antibiotics Penicillins:
Penicillin Potassium Industrial Salt – The quotation of mainstream factories is stable. Downstream purchasers buy according to demand. The market expectation is average. The transaction price is running within a narrow range (the transaction price is 112 – 120 yuan per billion units), and the market price index remains stable.
Amoxicillin – The quotations of mainstream factories are stable. The trade channels are affected by the suppliers’ inventory control, resulting in an extended supply cycle. Market attention continues to increase (transaction price is 220 – 245 yuan/kg), and the market price index is fluctuating with an upward bias in this period.
Amphenicols:
Florfenicol – Mainstream factories maintain production restrictions, market inventory is low, prices are relatively stable (transaction price is 183 – 205 yuan/kg), there is a strong wait – and – see sentiment in trade, terminal demand is light, and the market price index fluctuates and stabilizes this period.
Tetracyclines:
Oxytetracycline, Oxytetracycline Hydrochloride – Mainstream factories continue to increase prices and limit signing. Recently, the trade spot is in short supply, the market transaction quotation is firm, and the market price index has increased this period (oxytetracycline transaction at 75 – 85 yuan/kg, oxytetracycline hydrochloride transaction at 93 – 105 yuan/kg).
Doxycycline hydrochloride (Vibramycin) – Recently, the supply from factories has been average. Affected by the price support of upstream raw materials, the trade channels have a higher willingness to build inventories. The supply and procurement at the terminal are smooth and stable (the transaction price is 355 – 370 yuan/kg), and the market price index is fluctuating and stabilizing.
Macrolides:
Erythromycin Thiocyanate – Mainstream factories continue to limit supply, trade inventory is average, supply is insufficient, the central price of transactions is firm (transacted at 480 – 515 yuan/kg), and the market price index has increased this period.
Tylosin, Tilmicosin, Tylvalosin – The strategy of mainstream factories to suspend quotations and maintain prices continues. Market inventory is limited, prices are at a high level, and inquiry and procurement in the trading market have slowed down (market price of Tylosin Tartrate is around 305 yuan/kg, Tilmicosin Phosphate is around 345 yuan/kg, Tilmicosin is around 380 yuan/kg, Tylvalosin is around 435 yuan/kg, Tiamulin is around 245 yuan/kg). The market is highly concerned, and the market price index is operating relatively strongly this period.
Aminoglycosides:
Streptomycin Sulfate — The quotation of mainstream factories remains stable. Supported by rigid demand, the inquiry and procurement in the trading market are light (the transaction price is 272 – 290 yuan/billion units), and the market price index remains stable.
Apramycin Sulfate – The quoted prices of mainstream factories are stable. The inventory in the trading market is relatively low, and the market transaction prices are stable (transactions range from 198 to 220 yuan/kg). The market price index remains stable this period.
Neomycin Sulfate – Mainstream factories continue to limit signing and uphold prices. The trading channels make narrow adjustments according to their own inventories. There is a slight shortage of market spot goods. The transaction price is running at a high level (transactions are at 155 – 170 yuan per billion units), and the market price index is oscillating and stabilizing this period.
Gentamicin Sulfate – The supply channels of mainstream factories are relatively concentrated. The market attention for veterinary products is low. Transactions are made through price negotiation in the market (veterinary products are transacted at 1480 – 1520 yuan per billion units), and the market price index shows weakness.
Sulfonamides:
The upstream supply of sulfonamide varieties is relatively concentrated. The prices of most varieties are running steadily. Market inquiries and purchases are average, and the market price index is fluctuating and consolidating. (Sulfachloropyrazine sodium is around 220 yuan/kg, Sulfachlorpyridazine sodium is around 175 yuan/kg, and Sulfamonomethoxine sodium is around 190 yuan/kg)
Quinolones:
Enrofloxacin and ciprofloxacin – The mainstream production capacity is relatively concentrated. Due to the increase in upstream raw material costs, mainstream factories have maintained prices after the holiday, leading to a sharp increase in market attention (Enrofloxacin hydrochloride is traded at around 190 yuan/kg, and ciprofloxacin hydrochloride is traded at around 180 yuan/kg). The market price index remains stable.
Antipyretic and Analgesic Category:
Metamizole Sodium — Due to the increase in the prices of multiple upstream basic raw materials, the production cost has increased. Mainstream factories have raised prices, the circulating supply is relatively concentrated, and the market price index has increased (transacted at 88 – 100 yuan/kg).
Paracetamol – The production capacity of domestic mainstream factories is relatively concentrated, the price is operating within a narrow range (transacted at 25 – 35 yuan/kg), and the market price index remains stable.
Carbasalate Calcium – The quotation of mainstream factories remains stable, the market inquiry and procurement are basically stable, the market attention is relatively high (the transaction price is 36 – 45 yuan/kg), and the market price index is fluctuating.
Mequindox (Dihydroxy Methylenequine):
The mainstream factory agreements remain firm and continuous. Positive news of previous supply restrictions to support prices has been released. The trading channels are actively building positions, and the transaction prices have been steadily rising. Recently, the market transactions have slowed down, and the prices have been fluctuating and consolidating (with transactions at 39 – 49 yuan/kg). The market price index for this period has been fluctuating and stabilizing.
Colistin Sulfate:
The quotations of mainstream factories are stable. The supply and procurement in the trading market are average. The transaction price is running in a narrow range (the transaction price is 113 – 120 yuan/kg). The market price index of this period is fluctuating and stabilizing.
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