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Premium Pharmaceutical Grade N-(4-Aminobenzoyl)-L-glutamic Acid - Your Trusted Source
Kaifeng Darui Pharmaceutical Co., Ltd. stands as a leading manufacturer and supplier of premium pharmaceutical grade N-(4-Aminobenzoyl)-L-glutamic Acid (CAS No. 4271-30-1), also known as pABG or PABA-Glu. As a national high-tech enterprise integrating research, development, production, and sales of pharmaceutical raw materials, we deliver exceptional quality N-(4-Aminobenzoyl)-L-glutamic Acid that meets the most stringent international standards and specifications.
Our pharmaceutical grade N-(4-Aminobenzoyl)-L-glutamic Acid is produced in state-of-the-art GMP-certified facilities, ensuring consistent purity, potency, and performance for your pharmaceutical research, folic acid synthesis, and other specialized applications. With our advanced manufacturing processes and rigorous quality control systems, we guarantee a reliable supply of high-quality N-(4-Aminobenzoyl)-L-glutamic Acid that supports your product development and manufacturing needs.
N-(4-Aminobenzoyl)-L-glutamic Acid Properties and Specifications
N-(4-Aminobenzoyl)-L-glutamic Acid (CAS No. 4271-30-1) is a crucial intermediate in the biosynthesis of folic acid, with the molecular formula C₁₂H₁₄N₂O₅ and a molecular weight of 266.25 g/mol. Our pharmaceutical grade N-(4-Aminobenzoyl)-L-glutamic Acid appears as a white to off-white crystalline powder that is sparingly soluble in water but soluble in methanol, ethanol, and acetone.-L-glutamic%20Acid%20(CAS%204271-30-1)%20manufactured%20by%20Kaifeng%20Darui%20Pharmaceutical%20in%20GMP-certified%20facilities.jpg)
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Technical Specifications:
- Chemical Name: N-(4-Aminobenzoyl)-L-glutamic acid
- CAS Number: 4271-30-1
- Molecular Formula: C₁₂H₁₄N₂O₅
- Molecular Weight: 266.25 g/mol
- Appearance: White to off-white crystalline powder
- Purity: ≥ 97.0% (HPLC)
- Melting Point: 220-225°C
- pKa: 2.4 and 4.5 for the carboxylic and amino groups, respectively
- Solubility: Sparingly soluble in water, soluble in methanol, ethanol, and acetone
Our N-(4-Aminobenzoyl)-L-glutamic Acid meets or exceeds the requirements of various pharmacopeias and industry standards, making it suitable for global pharmaceutical applications. Each batch undergoes comprehensive testing using advanced analytical techniques, including HPLC, UV spectrophotometry, and other methods to ensure consistent quality and compliance with regulatory standards.
Applications and Benefits of Pharmaceutical Grade N-(4-Aminobenzoyl)-L-glutamic Acid
N-(4-Aminobenzoyl)-L-glutamic Acid is a versatile compound with numerous applications across pharmaceutical research and manufacturing. As a critical intermediate in folic acid synthesis and a valuable building block for various bioactive compounds, N-(4-Aminobenzoyl)-L-glutamic Acid plays an essential role in multiple pharmaceutical processes.
Folic Acid Synthesis:
N-(4-Aminobenzoyl)-L-glutamic Acid serves as a crucial intermediate in the synthesis of folic acid and its derivatives. Folic acid is a water-soluble B-vitamin that plays a vital role in cell division, DNA synthesis, and red blood cell formation. The synthesis of folic acid from N-(4-Aminobenzoyl)-L-glutamic Acid involves several steps, including condensation with p-aminobenzoic acid (PABA) to form dihydropteroic acid (DHP), which is then converted to tetrahydrofolic acid (THF), the active form of folic acid required for the biosynthesis of nucleic acids and amino acids.
Analytical Applications:
N-(4-Aminobenzoyl)-L-glutamic Acid is used as a strong UV absorbing tag for the derivatization of oligosaccharides to enhance their detection in analytical methods. This application is particularly valuable in research settings where precise detection and quantification of oligosaccharides are required.
Pharmaceutical Research:
As a metabolite of tetrahydrofolate, N-(4-Aminobenzoyl)-L-glutamic Acid is used in pharmaceutical research to study folate metabolism and related biochemical pathways. Researchers use high-purity N-(4-Aminobenzoyl)-L-glutamic Acid to investigate various aspects of folate-dependent processes and develop new therapeutic approaches.
Building Block for Bioactive Compounds:
N-(4-Aminobenzoyl)-L-glutamic Acid serves as a starting material for the synthesis of other bioactive compounds, including glutamate receptor agonists or antagonists, which are potential drug candidates for the treatment of neurological disorders such as Alzheimer's disease and epilepsy.
Manufacturing Excellence at Kaifeng Darui Pharmaceutical
Established in 2020 and located in Kaifeng Fine Chemical Park, Kaifeng Darui Pharmaceutical Co., Ltd. has rapidly emerged as a high-tech enterprise specializing in the production of pharmaceutical raw materials, food additives, and veterinary APIs. Our state-of-the-art manufacturing facilities span 700 square meters and operate in compliance with GMP standards, featuring Grade D cleanroom-certified API workshops.
Our N-(4-Aminobenzoyl)-L-glutamic Acid production process incorporates advanced technologies and equipment, including Shimadzu HPLC systems, Fourier-transform IR spectrometers, stability test chambers, and specialized distillation units. These sophisticated systems enable us to maintain precise control over every aspect of the manufacturing process, ensuring consistent product quality and purity.
The synthesis of N-(4-Aminobenzoyl)-L-glutamic Acid at our facilities follows a carefully optimized process involving the reaction of L-glutamic acid with 4-aminobenzoic acid (PABA) in the presence of coupling agents such as dicyclohexylcarbodiimide (DCC) or N,N'-diisopropylcarbodiimide (DIC). The reaction yields N-(4-Aminobenzoyl)-L-glutamic Acid and byproducts, which are separated through filtration. The purity of the product is further improved through recrystallization from suitable solvents such as methanol or water.
Environmental sustainability is a core value at Kaifeng Darui Pharmaceutical. Our facilities are equipped with 150t/d wastewater treatment capabilities and RCO exhaust systems, demonstrating our commitment to green manufacturing practices. By implementing these eco-friendly solutions, we minimize our environmental footprint while producing high-quality pharmaceutical ingredients.
Quality assurance is paramount in our operations. Our dedicated QC laboratories conduct comprehensive testing via HPLC, GC, UV-Vis spectrophotometry, and other analytical methods to ensure 100% compliance with international standards. Each batch of N-(4-Aminobenzoyl)-L-glutamic Acid undergoes rigorous testing for identity, purity, potency, and microbiological quality before release.
Custom Production and Processing Services
At Kaifeng Darui Pharmaceutical, we understand that different clients have unique requirements for their N-(4-Aminobenzoyl)-L-glutamic Acid supply. That's why we offer comprehensive custom production and processing services tailored to your specific needs. Our flexible manufacturing capabilities allow us to adjust production parameters, purity levels, particle size distribution, and other characteristics to meet your exact specifications.
Our custom processing services include:
Specialized Purification: We can implement additional purification steps to achieve ultra-high purity levels for specialized applications, such as pharmaceutical research or analytical standards. Our advanced purification techniques ensure the removal of impurities while maintaining the structural integrity and potency of the N-(4-Aminobenzoyl)-L-glutamic Acid.
Particle Size Modification: For applications requiring specific particle size distributions, we offer milling, micronization, and granulation services. These processes can optimize the flow properties, dissolution rate, and performance of N-(4-Aminobenzoyl)-L-glutamic Acid in your formulations or analytical methods.
Custom Stability Enhancements: We can incorporate stabilization techniques to improve the shelf life and stability of N-(4-Aminobenzoyl)-L-glutamic Acid under various storage conditions. These enhancements are particularly valuable for products destined for markets with challenging environmental conditions or requiring extended shelf life.
Analytical Method Development: Our R&D team can develop and validate custom analytical methods for your specific quality control requirements, ensuring that the N-(4-Aminobenzoyl)-L-glutamic Acid meets your unique specifications and regulatory needs.
Neutral Large Packaging Solutions
Kaifeng Darui Pharmaceutical offers versatile neutral large packaging solutions for our pharmaceutical grade N-(4-Aminobenzoyl)-L-glutamic Acid, designed to meet the diverse needs of our global clients. Our packaging options prioritize product protection, stability, and convenience while complying with international transportation regulations.
Our neutral large packaging options include:
Fiber Drums: Available in 10kg, 25kg, and 50kg sizes, our fiber drums with polyethylene liners provide excellent protection against moisture, light, and physical damage. These drums are ideal for bulk shipments and long-term storage of N-(4-Aminobenzoyl)-L-glutamic Acid.
Aluminum Foil Bags: For enhanced protection against light, moisture, and oxygen, we offer multi-layer aluminum foil bags in various sizes. These bags are sealed under nitrogen to maintain product stability and are suitable for both intermediate and final packaging.
HDPE Containers: Our pharmaceutical-grade HDPE containers with tamper-evident seals are available in multiple sizes for convenient handling and storage. These containers provide robust protection and are suitable for direct use in manufacturing environments.
Custom Packaging Solutions: We can develop tailored packaging solutions based on your specific requirements, including custom labeling, specialized protective measures, and packaging configurations optimized for your handling and storage systems.
All our packaging materials are pharmaceutical grade and undergo rigorous testing to ensure compatibility with N-(4-Aminobenzoyl)-L-glutamic Acid. Each package is clearly labeled with product information, batch numbers, manufacturing and expiry dates, and storage instructions in compliance with international regulations.
Quality Certifications and Compliance
Kaifeng Darui Pharmaceutical maintains the highest standards of quality and compliance in the pharmaceutical industry. Our operations are guided by a comprehensive quality management system that ensures consistency, safety, and efficacy in every batch of N-(4-Aminobenzoyl)-L-glutamic Acid we produce.
Our quality certifications and compliance measures include:
- GMP (Good Manufacturing Practice) certification for pharmaceutical production
- ISO 9001:2015 Quality Management System certification
- National High-Tech Enterprise designation (2023)
- Henan Provincial Innovative SME recognition (2022)
- Strict adherence to international pharmacopeia standards
- Comprehensive documentation and traceability systems
- Regular internal and external audits of quality systems
These certifications and compliance measures reflect our unwavering commitment to quality and provide our customers with confidence in the safety, efficacy, and regulatory acceptability of our pharmaceutical grade N-(4-Aminobenzoyl)-L-glutamic Acid.
Global Supply Capabilities
As a leading manufacturer of pharmaceutical grade N-(4-Aminobenzoyl)-L-glutamic Acid, Kaifeng Darui Pharmaceutical has established robust global supply capabilities to serve clients worldwide. Our strategic location in China's Henan province, combined with efficient logistics partnerships, enables us to deliver high-quality N-(4-Aminobenzoyl)-L-glutamic Acid to international markets with reliability and competitive pricing.
Our global supply advantages include:
Scalable Production Capacity: With our advanced manufacturing facilities, we can scale production to meet varying demand levels, from small specialized orders to large-volume commercial requirements. This flexibility ensures consistent supply regardless of order size.
Reliable Delivery Timelines: Our streamlined production planning and logistics coordination enable us to maintain dependable delivery schedules, supporting your just-in-time inventory management and production planning.
Comprehensive Documentation: We provide complete documentation packages, including Certificates of Analysis, stability data, and regulatory information, facilitating smooth customs clearance and regulatory compliance in your local market.
Technical Support: Our technical team offers comprehensive support throughout the supply process, from initial specification development to post-delivery application assistance, ensuring optimal utilization of our N-(4-Aminobenzoyl)-L-glutamic Acid in your products or research.
Research and Innovation
Innovation drives our growth at Kaifeng Darui Pharmaceutical. Our dedicated R&D team, comprising over 20 specialists including senior engineers and associate professors, continuously works to improve our N-(4-Aminobenzoyl)-L-glutamic Acid production processes, enhance product quality, and develop new applications.
Our research initiatives focus on:
Process Optimization: Developing more efficient and environmentally friendly manufacturing processes for N-(4-Aminobenzoyl)-L-glutamic Acid, reducing energy consumption and waste generation while maintaining or improving product quality.
Stability Enhancement: Researching novel stabilization techniques to extend the shelf life of N-(4-Aminobenzoyl)-L-glutamic Acid under various storage conditions, particularly for challenging environments in global markets.
Application Development: Exploring new applications for pharmaceutical grade N-(4-Aminobenzoyl)-L-glutamic Acid in emerging therapeutic areas, analytical methods, and specialized formulations.
Analytical Method Advancement: Refining analytical methods for more precise characterization and quality control of N-(4-Aminobenzoyl)-L-glutamic Acid, ensuring consistent compliance with evolving regulatory standards.
Through these research efforts, we continuously enhance the value we provide to our customers and maintain our position as a leading innovator in the pharmaceutical raw materials industry.
Contact Kaifeng Darui Pharmaceutical
Partner with Kaifeng Darui Pharmaceutical for your pharmaceutical grade N-(4-Aminobenzoyl)-L-glutamic Acid needs and experience the difference that quality, reliability, and customer-focused service can make for your business. Our dedicated team is ready to discuss your specific requirements and develop a customized supply solution that supports your success.
Headquarters:
Kaifeng Fine Chemical Park
Henan, China
Contact Information:
Tel: +86-13837178289
Email: info@daruipharm.com
Website: https://daruipharm.com/
Contact us today to learn more about our premium pharmaceutical grade N-(4-Aminobenzoyl )-L-glutamic Acid (CAS No. 4271-30-1) and how our custom production, processing, and packaging solutions can benefit your business.
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